There was another near-discovery of the base pairing rules in early 1952.
2.
If DNA replication takes place in this state, the base pairing rule for DNA may be jeopardised causing a mutation.
3.
This use of nucleic acids is enabled by their strict base pairing rules, which cause only portions of strands with rational design of base sequences that will selectively assemble to form complex target structures with precisely controlled nanoscale features.
4.
Nucleic acid design has the advantage of being much computationally easier than protein design, because the simple base pairing rules are sufficient to predict a structure's energetic favorability, and detailed information about the overall three-dimensional folding of the structure is not required.
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